Introduction: since the existence of organization, organizational knowledge has been managed more informally than formal ways, done through a knowledge supporting culture, by trusting and managing the employees. The objective of this research article is to explore the knowledge effectiveness capabilities in large organizations and their impact on knowledge effectiveness. Knowledge management capabilities are explored with respect to infrastructure, structure, storage, dissemination, and application. KM effectiveness is defined in terms of improved communication, enhanced collaboration, improved employee skills, better decision making, and improved productivity.